Specifically, 44 patients were diagnosed with AGS, 20 patients were diagnosed with progressive familial intrahepatic cholestasis (PFIC), 15 patients were diagnosed with NHS, 3 patients were diagnosed with total parenteral nutrition (TPN) cholestasis, 3 patients were diagnosed with cholelithiasis, one patient was diagnosed with citrin deficiency, and 6 patients had cholestasis of unknown etiology. The gene discussed is SLC25A13; the disease is hyperinsulinemic hypoglycemia, familial, 4.