The biomarkers that have been evaluated in HCC are fucosyltransferase 1 (FUT1), beta-1,3-galactosyltransferase 5 (B3GALT5) [11], CUG triplet repeat-RNA binding protein 1 (CUGBP1) [12], death-associated protein kinase 1 (DAPK1) mRNA [12], transforming growth factor-beta 1 (TGF-β1) [13], squamous cell carcinoma antigen (SCCA), serum anti-p53, hepatocyte growth factor [14], alpha-fetoprotein (AFP) [13-15], des-gamma-carboxyprothrombin (DCP) [14,15], and Golgi protein 73 (GP73) [13,14]. Here, ACE is linked to hepatocellular carcinoma.