TYRP1 and oculocutaneous albinism type 3: Kamaraj and Purohit also showed R326H and R356Q resulting in rigidity of tyrosinase-related protein-1 (TYRP1) protein which might disturb the structural conformation and catalytic function of the structure and also play a significant role in inducing Oculocutaneous albinism type III (OCA3) [46].