In the setting of Caucasian myositis patients, anti-PM/Scl autoantibody was strongly associated with HLA − DQB1∗02 : 01, anti-Jo-1 with HLA − B∗08 : 01, and HLA − DRB1∗03 : 01 alleles [14]. The gene discussed is PRB1; the disease is myositis disease.