Numerous studies have indicated that NK cells have a definite antitumor effect in the lung cancer (Bhome et al., 2015) and dendritic cells (DCs), as powerful antigen-presenting cells, play important roles in inducing the immune response of CD8+T cells (Hegde et al., 2020; Maier et al., 2020). The gene discussed is CD8A; the disease is lung cancer.