Studies have shown that m6A suppression can promote the proliferation and invasion of gastric cancer cells by activating the Wnt and PI3K-Akt signaling pathways Furthermore, Xia et al found that the m6A-related gene METTL3 was highly expressed in pancreatic tumor cells, and METTL3 knockdown could inhibit the proliferation and migration of tumor cells (Xia et al., 2019). This evidence concerns the gene METTL3 and gastric cancer.