TP53 and Miyoshi myopathy: We evaluated the anti-MM activity of HDS in MM cell lines (p53 wild-type: H929 and MM.1 S; p53 mutant: RPMI 8226, OCI-MY5, OPM2 and U266; p53 null: ARP-1) and two bortezomib-resistant MM cell lines (H929R and RPMI 8226/R5).