Regarding the peripheral blood biomarkers, the value of hemoglobin and albumin was lower in CRC subjects compared with non-CRC subjects, and the number of platelets was obviously increased in CRC patients compared with non-CRC subjects, but no considerably difference between CRC and non-CRC subjects regarding the number of white blood cell, neutrophil and lymphocyte (P > 0.05). This evidence concerns the gene ALB and colorectal carcinoma.