CDKN2B-AS1 and liver cancer: At least some of the downregulated lncRNAs (Fig. 1D, E) were previously found to be highly expressed in liver cancer and to promote proliferation and metastasis (AOC4P, PVT1, DANCR, DBH-AS1, HOXD-AS1, HNF1A-AS1, ANRIL)20–24.