Studies have shown [25] that HER-2 gene amplification, RNA and protein overexpression are common in gastric cancer, but these cannot be detected in non-cancer tissues, indicating that HER-2 plays an important role in the process of angiogenesis, invasion, and metastasis, and can affect the proliferation, differentiation, metastasis and adhesion of tumor cells. Here, ERBB2 is linked to cancer.