Therefore, it can be inferred that the abnormal elevation of the immunohistochemical marker HER-2 may indicate the occurrence of early gastric cancer or precancerous lesions, which can assist in the early diagnosis of gastric cancer, and contribute to the accurate evaluation of clinical staging, judgment of lymph node metastasis and prognosis. Here, ERBB2 is linked to metastatic malignant neoplasm in the lymph nodes.