CXCL12 and ovarian cancer: At present, although there is no specific study on the effect of bevacizumab combined with chemotherapy on SDF-1 and CXCR4 in epithelial ovarian cancer, there are reports related to SDF-1 and CXCR4 which suggest that the expression of SDF-1 and CXCR4 is upregulated in ovarian cancer patients’ tissues by immunohistochemistry.