Analysis of clinical scores (Fig. 2D) and thickness of epidermis (Fig. 2E) showed that the dermatitis was severer and epidermis was thicker in IL-32-Tg-control mice than that in WT control mice; similar changing tendency was observed in comparison between the IL-32-Tg-PA mice and WT-PA mice as well as between PA-induced mice and mice without PA treatment. The gene discussed is IL32; the disease is skin disorder.