Enhanced expression of PLIN2 correlated with disease progression, from ductal carcinoma in situ (DCIS) to invasive ductal carcinoma and to lymph node macrometastases (p = 0.0008) (Figure 7C) and for advanced stages of breast cancer (p = 0.001) (Figure 7D). The gene discussed is PLIN2; the disease is invasive ductal breast carcinoma.