BRCA1 and ovarian cancer: The use of PARP inhibitors has been most successfully exploited in BRCA1/2-deficient breast and ovarian cancers (Sonnenblick et al., 2015), and recently olaparib has been approved for the treatment of metastatic castration resistant prostate cancer (mCRPC) in patients with DDR gene mutations (de Bono et al., 2020; Hussain et al., 2020).