This retrospective, observational, single-center study included consecutivepatients with an anatomopathological diagnosis of conjunctival melanoma,registered between January 1992 and December 2019.BRAF/NRAS mutations were analyzed usingcobas®4800 kit (Roche®) in samplesobtained by excisional or map biopsy. The gene discussed is NRAS; the disease is malignant conjunctival melanoma.