To investigate how B12 impacts BAF during infection, the solubility of BAF in HEK293T (Fig. 10D) and HeLa (Fig. 10E) cells was examined during infection with either B12-deficient (vΔB12) virus or the revertant virus expressing N-terminal TAP-tagged B12 from its natural locus (vTAP-B12). The gene discussed is BANF1; the disease is infection.