XBP1 and breast cancer: As determined using the ROC Plotter tool based on 2108 BC patients treated with chemotherapy, AUC of chemotherapy response of XBP1 is 0.569 with P-value < 4.10E-05, which is similar to the genes which are known as chemotherapy resistance-related genes (Table 5), demonstrated predictive value of published biomarkers for chemotherapy response in BC using ROC Plotter [6,31–52].