ESR1 and breast carcinoma: It has an inhibitory potential towards tyrosinase, which is a multifunctional copper-containing enzyme essential for melanin biosynthesis in animals and plants.59 Muthyala et al. reported the hydrogenated form of isolongifolenone as a critical ingredient for the preparation of chiral ligand for estrogen receptor, which could be expedient in prevention and treatment of breast cancer and other gynecological issues.60 2-Methoxy-phenol, otherwise commonly known as guaiacol, is a methoxy group capped phenolic compound and is the monomethyl ether of catechol.