CRP and Insulin resistance: But several researchers suggested that an augmented level of CRP is directly linked with insulin resistance, obesity, glucose tolerance, BGL, and the etiology of type II DM; the same result was observed in the STZ-induced type II DM group, and WEL treatment significantly (P < 0.001) decreased the CRP level.54,55 The regeneration of pancreatic β-cells suggests the antidiabetic effect of WEL.