BAG6 and Alzheimer disease: To determine if BAG6 is specific to TDP43219 and TDP43247 or if it plays a general role in preventing intracellular aggregation of proteolytic fragments with solvent-exposed hydrophobicity, we examined its capacity to interact with TDP43208 (amino acids 208–247) and proteolytic fragments linked to AD (Lauritzen et al., 2016; Nunan et al., 2001, 2003).