In hepatocellular carcinoma (HCC), the cancer-testis lncRNA-CTHCC promotes HCC growth and metastasis, and mechanistically, lncRNA-CTHCC is modified by m6A methylation with METTL3 and IGF2BP1/IGF2BP3 to maintain its stability and increase its expression 192. This evidence concerns the gene METTL3 and hepatocellular carcinoma.