By using the high-throughput RNA sequencing, we identify that 413 lncRNAs (plus or minus two-fold to ninefold) are differentially expressed in WT and Smad3 KO kidneys of anti-glomerular basement membranous glomerulonephritis (anti-GBM GN), of them, 21 Smad3-dependent common lncRNAs are altered in both UUO and anti-GBM GN models 100. This evidence concerns the gene SMAD3 and glioblastoma.