Immunohistochemical staining detected a significant expression of UCP1, in the adenosis sample (normal breast control), on the mammary gland tube (Fig. 1G, red arrow, 100X and 400X), and a rare expression in invasive ductal carcinoma (Fig. 1H, 100X and 400X), a malignant subtype breast cancer with poor prognosis. Here, UCP1 is linked to invasive ductal breast carcinoma.