We compared CXCL2 knockdown with SNAIL knockdown, CXCL2 knockdown with SNAIL overexpression, CXCL2 overexpression with SNAIL knockdown and CXCL2 overexpression with SNAIL overexpression found that CXCL2 function and expression were sufficient to affect the migration and proliferation of tumours under coculture conditions (see Figure 5A-G). This evidence concerns the gene SNAI1 and neoplasm.