We transfected with gastric cancer cell lines with miR-193a-3p and transfected supernatant was collected to co-culture with 3T3-L1, the adipogenesis specific genes C/EBPα, PPARγ and Perilipin-1 were evidently elevated, and DLK1 was down-regulated in mimic group. This evidence concerns the gene PLIN1 and gastric cancer.