The toxicity profile of BGB includes nausea, fatigue, diarrhea, elevated lipase, dyspnoea, hypertension, hypoxia, pneumonia, elevated amylase, fatigue, pulmonary embolism, elevated ALT, hyponatraemia and hypophosphatemia.30 We are illuminating the way towards further developing ALK inhibitors with lower side effects. The gene discussed is GPT; the disease is hypophosphatemia.