CD36 and cardiovascular disorder: ox-LDL can stimulate CD36 expression, then the up-regulation of CD36 make more ox-LDL endocytosed, and eventually lead to excess cholesterol buildup to form foam cells.6 Growing evidence establishes that the imbalanced expressions of CD36, ABCA1, ABCG1 and SR-B1 mediate the foam cell formation via impairing the balance of cholesterol influx and efflux.7 Furthermore, oxidative stress and inflammation play important roles in the pathogenesis of diverse cardiovascular diseases including AS.