AFP is a typical gold marker diagnosed in the serum of HCC patients and germ cell malignancies.40 Elevated levels of AFP were seen in the Wistar rats when presented to hepatocarcinogen, which is a glycoprotein whose molecular weight is 70 kDa, situated at chromosome 4q11-q13, showing allelic losses in liver cancer. The gene discussed is AFP; the disease is hepatocellular carcinoma.