Xanthosine was related to the following pathways: Metabolism (Pw10), Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation (Pw21), Defective HK1 causes hexokinase deficiency (HK deficiency) (Pw46) and Interleukin-12 family signaling (Pw52). The gene discussed is SOAT1; the disease is hyperinsulinemic hypoglycemia, familial, 4.