Previously, other researchers demonstrated that etoposide induces a decrease in glucose uptake by Hodgkin's lymphoma cells possible through downregulating glucose transporters [46]; also, there has been described that genotoxic exposure inhibits the expression of both GLUT1 and GLUT3 genes [47], Similar discovers were described for Rapamycin, specifically rapamycin reduces glucose uptake in human adipocytes [48], and in CTLs cells rapamycin caused an approximate 50% reduction in levels of GLUT1 and GLUT3 [49]. This evidence concerns the gene SLC2A1 and Hodgkins lymphoma.