SCLC and NOTCH pathway genes such as ASCL1, DLK1, CEACAM5, SST, CHGB, NCAM1, TP73, EEF1A2, TMSB15A, INA and HEY1 showed lowest expression in the B-SqCC NE- region, intermediate expression in the PB-SqCC NE+ region and highest expression in the SCLC region. This evidence concerns the gene ASCL1 and small cell lung carcinoma.