Consistent with these findings, targeted transcriptomic NanoString analysis of tumor-infiltrating leukocytes revealed that pro-inflammatory cytokine and chemokine genes Ifng, Il-12b, Il-22, Cxcl9 and Cxcl10 were upregulated in infiltrating leukocytes from NI-1701-treated tumors. This evidence concerns the gene CXCL9 and neoplasm.