It was seen that mRNA expression of TLR3 (fold change = 1.9, P = 0.027), TLR7 (fold change = 1.7, P = 0.047), TLR8 (fold change = 1.89, P = 0.029), and TLR9 (fold change = 1.7, P = 0.020) was significantly upregulated in the COVID-19-Group A versus COVID-19-Group C. However, transcript levels of TLRs did not have significant difference between COVID-19-Group A versus COVID-19-Group B as well as COVID-19-Group B versus COVID-19-Group C (data not shown). The gene discussed is TLR8; the disease is COVID-19.