The mRNA expression of TLR3 (fold change = 3.4, P = 0.032), TLR7 (fold change = 2.0, P = 0.041), TLR8 (fold change = 2.8, P = 0.019), and TLR9 (fold change = 2.1, P = 0.016) was significantly upregulated in COVID-19- Group A compared with the Control-Group I (Table 3). This evidence concerns the gene TLR8 and COVID-19.