TLR7 and COVID-19: There was a significant upregulation of mRNA of TLR3 (fold change = 2.1, P = 0.022), TLR7 (fold change = 1.9, P = 0.025), TLR8 (fold change = 2.0, P = 0.039), and TLR9 (fold change = 2.9, P = 0.024) in COVID-19-Group B compared with the Control-Group I (Table 3).