TLR8 and COVID-19: There was a significant upregulation of mRNA of TLR3 (fold change = 2.9, P = 0.011), TLR7 (fold change = 2.2, P = 0.020), TLR8 (fold change = 2.9, P = 0.040), and TLR9 (fold change = 2.5, P = 0.001) in COVID-19-Group A in comparison to the Control-Group II (Table 3).