The results showed that CRP (95% CI = 1.129–15.157, HR = 4.137, P = 0.032), CIMT (95% CI =1.104–11.932, HR = 3.629, P = 0.034), and SOX2-OT (95% CI = 1.200–13.984, HR = 4.096, P = 0.024) were independent risk factors for patients with atherosclerosis (Table 2). Here, SOX2 is linked to atherosclerosis.