LINC02500 and neoplasm: The integration event led to a 134,251 bp (chr4:182138890–182273142) loss of 4q34.3 region encompassing a long intergenic non-coding RNA (lincRNA) gene LINC02500. Another lincRNA gene LINC00290, located approximately 58.6 kb downstream of the breakpoint, was found to be expressed only in this tumor, but with no corresponding expression in the other tumors investigated (Supplementary Fig. 7).