We also found that STING deficiency reversed the increased heart weight/body weight ratio (HW/BW) and heart weight/tibia length ratio (HW/TL) in DCM mice (Fig. 2c, d), which indicated that knockdown of STING in the hearts of DCM mice had the potential to inhibit cardiac hypertrophy. This evidence concerns the gene STING1 and familial dilated cardiomyopathy.