These results implied that SY-707 regulates FAK and IGF1R signal transduction pathways to inhibit tumor cell growth and tumorgenesis via inhibiting the activities of these two kinases, meaning that proliferation-associated MAPK and AKT signaling pathways are keys of SY-707’s inhibition of the growth of FAK- or IGF1R-expressing cells. The gene discussed is PTK2; the disease is neoplasm.