Type II IFN (IFNγ) are key inducers of proinflammatory cytokines such as IRF1, IFIT1, CXCL10 [42] and crucially, known cellular receptors for ZIKV infection such as AXL, Tyro3, and DC-SIGN [43]. This evidence concerns the gene CXCL10 and Zika virus infectious disease.