Kaplan-Meier survival analyses performed using the cut-off values derived from ROC showed that patients with CI demonstrating high levels of RAGE in the AF (≥1.30 μg/mL; log-rank test, P < 0.001) or resistin (≥ 62.87 ng/mL; log-rank test, P = 0.048) undergoing emergency cerclage displayed significantly shorter intervals from cerclage to delivery (Fig 3). The gene discussed is AGER; the disease is atrial fibrillation.