For the prediction of the occurrence of SPTD at <34, the AUC values of AF PTX3, RAGE, and resistin were 0.749, 0.669, and 0.770, respectively (Table 4 and Fig 1), with no significant differences among them (all variables: P = 0.31–0.58), and no significant difference was observed compared to that in AF IL-6 (P = 0.30–0.68). This evidence concerns the gene RETN and atrial fibrillation.