Further analysis showed that IL-10 production did not correlate with either IFN-γ or IL-2 in HCs, while a significant but weak correlation existed between IFN-γ and IL-10 2 weeks (day 36) and 3 months (day 115) after the second dose in patients with IBD (Supplemental Figure 3). The gene discussed is IL10; the disease is inflammatory bowel disease.