CD40LG and B-cell chronic lymphocytic leukemia: In B-cell chronic lymphocytic leukemia (CLL), the miR-17∼92 cluster members were highly amplified, among which four (miR-17, miR-20a, miR-18a and miR-19b) and five (miR-17, miR-20a, miR-18a, miR-19a and miR-19b) members were significantly induced by CD154 and stromal cell culture, respectively [19].