The model excluded age, BMI, duration of disease, hepatic tumour load, Ki-67 of primary tumour, ejection duration, SEVR, AIx, central systolic pressure, central diastolic pressure, central pulse pressure, central end-systolic pressure, brachial and aortic PWV, RHI, removal of primary tumour, use of somatostatin analogues, PRRT, fP-CgA, and P-proBNP. The gene discussed is NPPB; the disease is neoplasm.