We assumed that HIVEP genes are expressed in an organ‐specific pattern during the developmental process, among which HIVEP2 and 3 exhibit the most divergent expression status between AML samples and normal tissues (3.000 ± 1.298 vs. 0.888 ± 0.116 for HIVEP2, p < 0.001; 3.203 ± 1.056 vs. 0.651 ± 0.126 for HIVEP3, p < 0.001). This evidence concerns the gene HIVEP3 and acute myeloid leukemia.