Transcriptome analysis of five MSI‐related genes (MSH2, MSH6, MLH1, PMS1, and PMS2) and five CRC‐related genes (BRAF, KRAS, APC, TP53, and CDX2) showed that CDX2 expression was most severely decreased in SSA/P. The gene discussed is PMS1; the disease is colorectal carcinoma.