SULT2A1 and polycystic ovary syndrome: In women without PCOS, two studies indicated significant DHEAS declines (Schmidt et al., 2011a; Forslund et al., 2021), while five studies (Palomba et al., 2007; Brown et al., 2011; Carmina et al., 2012b; Palomba et al., 2014; Udesen et al., 2019) indicated non-significant changes from baseline.