During the final stages of CGNP differentiation (light and dark blue clusters), processes related to neuronal connectivity, differentiation and regeneration are enriched, as well as major signal transduction routes like Bmp, TGF-β and phosphoinositide 3-kinase (PI3K) signaling, which are also known to play a role in medulloblastoma (Angley et al., 2003; Grimmer and Weiss, 2008; Northcott et al., 2012b). Here, TGFB1 is linked to medulloblastoma.