APOA1 and infection: The metabolomic profiles observed in this study in infants with greater infection burden (higher triglycerides, lower HDL cholesterol, and lower ApoA1) reflect those previously linked to infection, including SARS-CoV-2 (Alvarez and Ramos, 1986; Bruzzone et al., 2020; Gallin et al., 1969; Liuba et al., 2003; Madsen et al., 2018), and CVD risk (particularly higher phenylalanine) in adults (Würtz et al., 2015; Würtz et al., 2012).