NFKB1 and cancer: The immune cells in the TME play vital roles in the tumor progression, for example, tumor‐associated macrophages (TAMs) and myeloid‐derived suppressor cells (MDSCs) promote tumor invasion and contribute to therapeutic inefficacy in many cancer types, and cancer‐associated fibroblasts (CAFs) enhance tumorigenesis by secreting growth factors and activating NF‐κB signaling pathway.8