Among these ELANE, NLRP6, CASP4, SCAF11, PRKACA, CASP6, CASP9, AIM2, NLRP7, GPX4, NOD2, TIRAP, PJVK, CASP3, NOD1, CASP8, GSDMD, NLRP1, GSDME, GSDMB, PYCARD, PLCG1, and GSDMC were upregulated in tumor than normal, while IL6, IL1B, and NLRP3 were downregulated (Figure 1). Here, CASP4 is linked to neoplasm.