NFKB1 and cancer: Nuclear factor-κB (NF-κB) is a family of transcription factors that plays a critical role in inflammation, immunity, cell proliferation, tumor-associated angiogenesis, and metastasis [7, 8] The NF-κB pathway is of particular interest in cancer metastasis, as it can bind the transcription of several target genes that promote invasion and metastasis [9].